Updating on the pathogenesis of systemic lupus erythematosus
If MSU crystals are absent, other criteria, including serum urate levels, are needed for a diagnosis.
A high titer of serum urate is consistent with gout if other clinical or imaging criteria are met.
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Small children often do not exhibit the aforementioned symptoms, and may only be irritable and look unwell.Inoltrenei pazienti di razza nera con LES si evidenzia una pi elevata prevalenza e severit della glomerulonefrite o della insufficienza renale. Fattori genetici potrebbero giocare un ruolo importante nella eziopatogenesi del LES.Un supporto a tale concetto proviene dall'osservazione di una elevata prevalenza di LES in gemelli monozigoti.Autoimmune rheumatic diseases (ARDs) are diseases in which the immune system attacks the joints and certain systems. ARDs are sometimes difficult to distinguish due to overlapping signs and symptoms: joint pain, diminished joint mobility, rash, fever, malaise, fatigue, and weight loss.Laboratory testing may be useful for the differential diagnosis and classification.